WebJan 16, 2004 · The first total synthesis of (+)-phomopsidin has been achieved via a diastereoselective transannular Diels−Alder (TADA) reaction. Key steps in the synthesis … WebJan 24, 2009 · In 1997, (+)-phomopsidin ( Fig. 1) was isolated from a marine-derived fungus, Phomopsis sp. strain TUF 95F47, that was collected in Pohnpei. 1 (+)-Phomopsidin was found to be a new inhibitor of microtubule assembly, showing strong inhibitory activity against the assembly of microtubule proteins derived from the porcine brain at an IC 50 of …
Isolation and characterization of bioactive metabolites …
WebThey were isolated as major constituents of the stromata of Hypoxylon carneum, a species that had shown a highly specific secondary metabolite profile in a survey of xylariaceous ascomycetes based on HPLC profiling. Their chemical structures were elucidated by a combination of spectroscopic methods and by preparation of derivatives. WebJan 24, 2009 · In 1997, (+)-phomopsidin ( Fig. 1) was isolated from a marine-derived fungus, Phomopsis sp. strain TUF 95F47, that was collected in Pohnpei. 1 (+)-Phomopsidin was … on tv reviews
Carneic Acids A and B, Chemotaxonomically Significant …
WebJun 11, 2024 · Perï¬ uoroalkanes Graham Sandford Department of Chemistry, University of Durham, South Road, Durham DH1 3LE, UK Tetrahedron 59 (2003) 437 Absolute structure, biosynthesis, and anti-microtubule activity of phomopsidin, isolated from a marine-derived fungus Phomopsis sp. Hisayoshi Kobayashi,a,* Shiori Meguro,b Takeshi Yoshimotob and … WebApr 24, 2024 · During a survey of xylarialean fungi in Northern Iran, several specimens that showed affinities to the Hypoxylon rubiginosum complex were collected and cultured. A comparison of their morphological characters, combined with a chemotaxonomic study based on high performance liquid chromatography, coupled with diode array detection … WebJan 24, 2009 · This manuscript describes an alternative synthetic approach for (+)-phomopsidin, which shows strong inhibitory activity against the assembly of microtubule proteins. We observed that the TADA... on tv sacramento