WebMar 11, 2024 · TMexCD1-TOprJ1 was found to be capable of excreting multiple antimicrobials, including tigecycline, which contributed to the strain's resistance. In this study, we identified K. pneumoniae... WebInformation for Medical Professionals Index to Diseases and Injuries. References found for the code V01.1 in the Index of Diseases and Injuries: Contact SEE ALSO See Also A “see …
Characterization of IncHI1B Plasmids Encoding Efflux Pump
WebCarbapenems, tigecycline and colistin are three important antimicrobial agents for the treatment of clinical infections caused by multidrug-resistant Enterobacteriaceae. Here we characterised the formation of hybrid plasmids containing mcr-8 and bla NDM-1 or tmexCD1-toprJ1 that could confer resistance to colistin and carbapenems or tigecycline. WebMay 5, 2024 · The discovery of plasmid-mediated tet (X) variants and efflux pump gene tmexCD1-toprJ1 conferring bacteria resistance to tigecycline has compromised glycylcycline as the last line of defense against infection, which poses serious threat to … ottonote caffè
Emergence and Inter- and Intrahost Evolution of Pandrug …
WebMar 15, 2024 · Tigecycline and carbapenems are a few of the last-resort antimicrobial agents used to treat serious infections caused by MDR bacteria. 1–3 However, the emergence of mobile tigecycline and carbapenem … WebJun 1, 2024 · The plasmid-encoded resistance-nodulation-division (RND) efflux pump gene cluster tmexCD1-toprJ1 was first reported in 2024 [14] and was located on a conjugative IncFIA-type plasmid pHNAH8I in K. pneumoniae isolated from cloacal swab samples from a chicken farm in China in 2024. WebMar 21, 2024 · The tmexCD1-toprJ1 and blaNDM-1 -carrying plasmids (pKP19-3088-375k and pKP19-3023-374k) in both isolates could not be transferred horizontally. Open in a … ottonotinpo